Age
and aging

Graham Jackson
Consultant Cardiologist, Guy’s and St Thomas’ Hospitals NHS Trust,
Cardiothoracic Centre, St Thomas’ Hospital, London, UK
Correspondence: Dr Graham Jackson, Guy’s and St Thomas’ Hospitals
NHS Trust, Cardiothoracic Centre, 6th Floor East Wing, St Thomas’
Hospital, Lambeth Palace Road, London SE1 7EH, UK. Tel: +44 20
7928 9292, fax: +44 20 7960 5680, e-mail:
lilian.crossley@gstt.sthames.nhs.uk
Health care of the elderly assumes ever-increasing
importance in developed countries as their populations age. With
age come serious illnesses and increased health care utilization
with important cost implications and the danger of practicing
ageism. Currently, worldwide, there are 380 million people aged
over 65 years of age, but by 2020 this figure will have risen
to 690 million, and deaths due to noncommunicable diseases (mainly
cardiovascular) will have risen to an overall figure of 49.7 million
from the current 28 million. The challenge of managing cardiovascular
disease in the elderly is important now, but can only increase
over time.
Cardiovascular risk increases with age, whether due to age alone
or combined with an increased incidence of diabetes, hypertension,
or, to a lesser degree, hyperlipidemia. As a result of a greater
overall risk, the potential for greater overall benefit from risk
factor modification has become a reality in the elderly.
Social factors are important. Women live longer than men and therefore
more often live alone and, in turn, are lonely. The elderly have
more concerns about money and may rely on less healthy foods and
spare themselves everyday conveniences such as proper heating.
In an increasingly violent society the elderly become more vulnerable
and may be afraid to go out and exercise, and, in turn, show a
greater reluc-tance to give up smoking, which becomes their indoor
recreation. Our medical advice must therefore be coupled with
community action. There is a need to improve the financial circumstances
of the elderly, to improve their environment (indoors and outdoors),
and to promote good health with easily accessible and tailored
healthy lifestyle options which are safe to pursue.
In this issue we are promoting cardiovascular health, and, importantly,
putting age and health in perspective. Age may alter myocardial
oxidative metabolism, but as Professor Gropler concludes, we need
to know the exact relevance to the elderly in the clinical context
because of the potentially important therapeutic implications.
The alterations in cardiac metabolism are reviewed by Professor
van der Vusse, and these also have implications for general advice
and prescribing. Safe prescribing in the elderly is an important
issue because of the changes in physiology and pharmacology that
occur with age, so the paper by Drs Wisniacki and Lye has great
practical relevance. Angina in the elderly is common, and in my
article I have tried to balance risk over benefit, taking into
account the needs and wishes of the individual.
Christopher Blauth brings a surgeon’s perspective to selecting
patients for surgery. The risks rise with age, so the selection
process must be individualized to that particular person’s risk.
The patient’s family also needs to be aware of the risks as well
as the benefits – fully informed consent is an essential part
of our medical practice. In addition, full agreement between surgeon
and cardiologist must be the key to optimizing management, so
a surgeon’s view is to be welcomed. Dr Meurin highlights the problem
of treating high-risk patients and, in discussing the management,
emphasizes the role of the metabolic agent trimetazidine as a
means of avoiding haemodynamic side-effects while relieving symptoms
and improving quality of life. Collectively in this issue the
authors put quality of life at the forefront of our approach to
treating elderly patients with cardiac disease.
We can only do so much for the elderly as health care professionals:
the elderly also need committed politicians, who will support
the social infrastructure, and strong family carers. The elderly
do not want to be a burden nor should they be. The community,
both medical and nonmedical, owes them that right.
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