Heart and Metabolism

Hypertrophic Cardiomyopathy

CONTENTS Number 21, 2003

	EDITORIAL Hypertrophic cardiomyopathies: role of genetic mutations in proteins involved in sarcomere function and energy metabolism in the pathogenesis of this disorder Gary Lopaschuk

	BASIC ARTICLE Cellular changes in hypertrophic cardiomyopathy Charles S. Redwood

	MAIN CLINICAL ARTICLE Clinical management of hypertrophic cardiomyopathy Rajesh Thaman, Jaymin Shah, William J. McKenna

	IMAGING Metabolic imaging of hypertrophic cardiomyopathy Eiji Tadamura

	NEW THERAPEUTIC APPROACHES New therapeutic approaches to hypertrophic cardiomyopathy: alcohol ablation Hubert Seggewiss, Angelos Rigopoulos

	FOCUS ON TRIMETAZIDINE (VASTAREL) Addressing the need for continuous round-the-clock cardioprotection with new Vastarel MR P. Meurin, T. Hénane

	CASE REPORT Hypertrophic cardiomyopathy Graham Jackson

	REFRESHER CORNER Genetics of hypertrophic cardiomyopathy W. E. M. Kok, M. J. H. Baars

	FEATURED RESEARCH Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes Efficacy of perindopril in reduction in cardiovascular events among patients with stable coronary artery disease Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T In vivo detection of cell death in the area at risk in acute myocardial infarction

	GLOSSARY Gary D. Lopaschuk

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