Number 69, 2016, Good fat or bad fat?

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  • EDITORIAL
    Burning fat to increase metabolic rates
    G. D. Lopaschuk
    Read the editorial
  • ORIGINAL ARTICLES
    Brown adipose tissue and the genetics of obesity
    Ande Satyanarayana, PhD
    Department of Biochemistry and Molecular Biology, Molecular Oncology & Biomarkers Program, Georgia Regents University Cancer Center, Georgia Regents University, Augusta, Georgia, USA
    Keywords: beige cells; brown fat; genetic mouse models; oxidative metabolism; PGC1α; thermogenesis; UCP1
  • ORIGINAL ARTICLES
    Integrated control of brown adipose tissue
    Emanuele Marzetti, MD, PhD1; Emanuela D’Angelo, MD1; Giulia Savera, BS1; Christiaan Leeuwenburgh, PhD2; Riccardo Calvani, PhD1
    1Department of Geriatrics, Neurosciences and Orthopedics, Teaching Hospital “Agostino Gemelli,” Rome, Italy 2Department of Aging and Geriatric Research, University of Florida, Gainesville, Florida, USA
    Keywords: adiposity; beige cells; diabetes mellitus; energy metabolism; inflammation; mitochondrial respiration; positron emission tomography (PET); sympathomimetics; weight loss
  • ORIGINAL ARTICLES
    Assessing brown adipose tissue in humans
    Yu-Shin Ding, PhD New York University School of Medicine, Departments of Radiology and Psychiatry, New York, NY, USA
    Keywords: brown adipose tissue; [11C]MRB; obesity; norepinephrine transporter; positron emission tomography (PET); sympathetic nervous system
  • ORIGINAL ARTICLES
    Brown adipose tissue as a potential therapeutic target in obesity therapy
    Niels Jessen, MD, PhD Research Laboratory for Biochemical Pathology, Department for Clinical Medicine, Aarhus University, Denmark
    Keywords: activators of thermogenesis; brown adipose tissue; obesity
  • ORIGINAL ARTICLES
    Benefits of trimetazidine (TMZ) in obese patients
    Fausto J. Pinto, FESC, FACC Lisbon University Medical School, University of Lisbon, Lisbon, Portugal
    Keywords: ischemic heart disease; obesity; trimetazidine
  • CASE REPORT
    Obesity and cardiovascular disease
    Giacinta Guarini, MD, PhD Cardiovascular Medicine Division, Cardio Thoracic and Vascular Department, University of Pisa, Italy
    Keywords: heart failure; obesity cardiomyopathy; obesity paradox
  • REFRESHER CORNER
    Uncoupling proteins as mediators of mitochondrial metabolic rates
    Gary D. Lopaschuk, PhD Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada
    Keywords: mitochondria; mitochondrial membrane potential; thermogenesis; uncoupling protein 1; uncoupling protein 3
  • HOT TOPICS
    Will PCSK9 inhibitors stand up to statins till the end?
    Alda Huqi, MD, PhD
  • GLOSSARY
    G. D. Lopaschuk