Number 76, 2018, The frail patient with heart disease: please handle with care!

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• EDITORIAL
  The frail patient with heart disease: please handle with care!
  D. Hausenloy
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• ORIGINAL ARTICLES
  The frail patient with heart disease: an emerging and challenging issue
  N. Veronese
  
  Keywords: cardiovascular disease; comprehensive geriatric assessment; frailty
  
• ORIGINAL ARTICLES
  Frailty, heart failure, and cognitive impairment: a triangle in elderly people
  K. Shinmura
  
  Keywords: cognitive impairment; elderly; physical frailty
  
• ORIGINAL ARTICLES
  Aortic stenosis in the frail patient: maximizing the benefit of TAVI
  A. Anand, N. L. Mills
  
  Keywords: aortic stenosis; frailty; TAVI
  
• ORIGINAL ARTICLES
  Cardiac surgery in the frail patient: managing the increased risks
  B.L. Y. Koh, N. C. Hwang
  
  Keywords: frailty; pathophysiology; pre-habilitation; sarcopenia
  
• ORIGINAL ARTICLES
  Trimetazidine in the frail patient
  C. Vitale, M. Fini, G. M. C. Rosano
  
  Keywords: cardiovascular disease; frailty
  
• CASE REPORT
  Managing the frail patient undergoing a percutaneous coronary intervention
  L. Candilio
  
  Keywords: elderly; frailty; heart team; multivessel coronary artery disease; percutaneous coronary intervention
  
• REFRESHER CORNER
  Energy metabolism in the aged heart
  G. D. Lopaschuk
  
  Keywords: fatty acid oxidation; glucose oxidation; glycolysis; mitochondria
  
• HOT TOPICS
  Exercise and diet for heart disease in the frail patient: fact or fiction?
  S. Nanayakkara, D. M. Kaye
  
  Keywords: frailty; heart disease; lifestyle intervention
  
• GLOSSARY
  G. D. Lopaschuk