Number 81, 2020, Myocardial Ischemia: From Disease to Syndrome

Number 80, 2019, Heart Failure in patients with Diabetes

Number 79, 2019, Revisiting Hypertension

Number 78, 2019, Stable angina: to stent or not to stent?


GLOSSARY
G. D. Lopaschuk
  • Number 77, 2018, The heart failure syndrome: only a matter of the heart?

    Number 75, 2018, Acute coronary syndromes: changing face

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    • EDITORIAL
      Acute coronary syndromes: changing face
      M. Marzilli
      Read the editorial
    • ORIGINAL ARTICLES
      The changing face of acute coronary syndromes
      S. Al Yaseen, A. Al Badri, J. Wei, C.Shufelt, N. Bairey Merz
      Keywords: acute coronary syndrome; non–ST-segment elevation myocardial infarction; stable ischemic heart disease; sex differences; ST-segment elevation myocardial infarction
    • ORIGINAL ARTICLES
      Acute coronary syndrome without coronary obstructions: diagnosis and treatment
      G. Niccoli, G. Scalone, F. Crea
      Keywords: acute myocardial infarction; microcirculation; no obstructive coronary atherosclerosis
    • ORIGINAL ARTICLES
      Does unstable angina still exist?
      C. A. Rambarat, I. Y. Elgendy, C. J. Pepine
      Keywords: myocardial infarction; troponin; unstable angina
    • ORIGINAL ARTICLES
      Acute coronary syndrome: the illusion of treatment!
      M. Marzilli
      Keywords: acute coronary syndrome; percutaneous coronary intervention; therapeutic illusion
    • ORIGINAL ARTICLES
      Focus on trimetazidine in acute coronary syndrome
      L. H. W. Gowdak
      Keywords: arrhythmia; myocardial infarction; prognosis; treatment; trimetazidine
    • CASE REPORT
      From atropine eye drops to takotsubo syndrome in an 89-year-old lady
      M. C. Scali, M. Marzilli
      Keywords: acute microvascular dysfunction; atropine; takotsubo syndrome
    • REFRESHER CORNER
      Cardiac energy metabolism in mild and severe ischemia
      G. D. Lopaschuk
      Keywords: fatty acid oxidation; glucose oxidation; glycolysis
    • HOT TOPICS
      False positive troponins
      M. Marber
      Keywords: acute coronary syndrome; biomarker; necrosis; troponin
    • GLOSSARY
      G. D. Lopaschuk

    Number 74, 2017, Heart failure in real life

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    • EDITORIAL
      Heart failure in real life
      M. Marber
      Read the editorial
    • ORIGINAL ARTICLES
      Assessing the breathless patient
      M. R. Cowie
      Keywords: diagnosis, heart failure; natriuretic peptide
    • ORIGINAL ARTICLES
      Heart failure with mid-range EF (HFmrEF): a mildly reduced EF does not imply a mild
      disease
      C. Tschöpe, B. Pieske
      Keywords: diagnostic, HFmrEF, pathophysiology, treatment
    • ORIGINAL ARTICLES
      Renal function in acute heart failure: what can go wrong and what we can do about it
      S. R. Goldsmith
      Keywords: acute heart failure, kidney, afterload/preload
    • ORIGINAL ARTICLES
      Preventing heart failure hospital readmissions: challenges and opportunities
      B. Ziaeian, G. C. Fonarow
      Keywords: heart failure, prevention, process measures, quality of care, readmission
    • ORIGINAL ARTICLES
      Clinical benefits of trimetazidine in heart failure
      G. M. C. Rosano
      Keywords: cardiac energy metabolism, heart failure, trimetazidine
    • CASE REPORT
      Team-based management to improve real-world outcomes in heart failure
      M. Ryan
      Keywords: Team-based management in heart failure
    • REFRESHER CORNER
      Cellular metabolic and structural changes in heart failure
      G. D. Lopaschuk
      Keywords: apoptosis, autophagy, excitation-contraction coupling, mitochondria, mitofission, mitofusion,mitophagy
    • HOT TOPICS
      Identifying heart failure in the emergency room
      M. C. Scali
      Keywords: B-line, emergency room, heart failure, lung comet
    • GLOSSARY
      G. D. Lopaschuk

    Number 73, 2017, Cardiovascular diseases and diabetes: causes and cures

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    • EDITORIAL
      Diabetes: getting to the heart of the matter.
      G. D. Lopaschuk
      Read the editorial
    • ORIGINAL ARTICLES
      Diabetes: the cost of globalization
      P. M. Nilsson, L. Bennet
      Keywords: costs, diabetes, global, lifestyle, migration, obesity

    • ORIGINAL ARTICLES
      Better glycemic control and cardiovascular outcomes
      G. D. Lopaschuk
      Keywords: antihyperglycemic agent, cardiovascular outcome, heart failure, type 2 diabetes mellitus

    • ORIGINAL ARTICLES
      Treating myocardial ischemia in diabetics: drugs, surgery, and stents
      R. Belardinelli
      Keywords: chronic angina, diabetes mellitus, therapeutic strategy

    • ORIGINAL ARTICLES
      Early detection of left ventricular dysfunction in diabetes
      D. Y. Leung, M. Leung
      Keywords: cardiomyopathy, diabetes, echocardiography

    • ORIGINAL ARTICLES
      Clinical benefits of targeting cardiac cells directly with trimetazidine in patients with coronary disease and diabetes
      G. Fragasso, G. Anastasia, G. Monaca, G. Pinto
      Keywords: CAD, diabetes, myocardial metabolism, trimetazidine

    • CASE REPORT
      Managing chest pain in a diabetic patient
      M. C. Scali
      Keywords: B-lines, risk, stress-echo

    • REFRESHER CORNER
      Cardiac energy metabolism in diabetes
      K. L. Ho, J. R. Ussher
      Keywords: energy metabolism, fatty acid oxidation, glucose oxidation, type 1 diabetes, type 2 diabetes

    • HOT TOPICS
      Cardiovascular diseases and diabetes: causes and cures
      J. E. Salles
      Keywords:  

    • GLOSSARY
      G. D. Lopaschuk

    Number 72, 2017, Refractory angina

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    • EDITORIAL
      Living with pain
      L. H. W. Gowdak
      Read the editorial
    • ORIGINAL ARTICLES
      Refractory angina or inappropriate antianginal therapy?
      A. Huqi, M. Marzilli
      Keywords: CAD, guideline-directed medical therapy, persistent angina

    • ORIGINAL ARTICLES
      Prevalence of refractory angina in clinical practice
      L. H. W. Gowdak
      Keywords: optimal medical therapy, prevalence, refractory angina

    • ORIGINAL ARTICLES
      Prognostic implications of refractory angina
      P. G. Steg
      Keywords: angina, ischemia, prognosis

    • ORIGINAL ARTICLES
      Nonpharmacological approaches to refractory angina.
      R. Cheng, T. D. Henry
      Keywords: enhanced external counterpulsation, neuromodulation, PCI, refractory angina

    • ORIGINAL ARTICLES
      Clinical benefits of treating angina directly at the cardiac cell level with
      trimetazidine.
      I. Milinković, A. J. Coats, G. Rosano, Y. Lopatin, P. M. Seferović
      Keywords: antianginal, cardiomyocyte, trimetazidine

    • CASE REPORT
      The role of optimal medical therapy in patients with refractory angina
      L. H. W. Gowdak
      Keywords: angina, coronary artery disease, treatment

    • REFRESHER CORNER
      Estimating ischemic burden
      V. Agarwal, M. F. Di Carli
      Keywords: coronary flow reserve (CFR), ischemic burden, multimodality cardiac imaging

    • HOT TOPICS
      Errare humanum est, perseverare autem diabolicum
      A. Huqi
      Keywords: comparative effectiveness of noninvasive diagnostic strategies, coronary artery disease, ischemic heart disease, percutaneous coronary intervention

    • GLOSSARY
      G. D. Lopaschuk

    Number 71, 2016, Heart failure with preserved ejection fraction (HFpEF): what’s the problem?

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    • EDITORIAL
      HFpEF, is it more than just the sum of its parts?
      M. Marber
      Read the editorial
    • ORIGINAL ARTICLES
      Heart failure with preserved ejection fraction (HFpEF): a basic and clinical perspective.
      A. Shah, P. C. Chowienczyk
      Keywords: diastolic dysfunction, HFpEF, ventricular-vascular coupling
    • ORIGINAL ARTICLES
      How to diagnose heart failure with preserved ejection fraction.
      T. H. Marwick
      Keywords: diagnosis, diastolic dysfunction, heart failure with preserved ejection fraction

    • ORIGINAL ARTICLES
      Treatment of HFpEF: why we have no evidence.
      M. Marber
      Keywords: HFpEF, left ventricular ejection fraction

    • ORIGINAL ARTICLES
      Imaging fibrosis in heart failure with preserved ejection fraction.
      A. N. Bhuva, R. Schofield, R. T. Lumbers, C. H. Manisty, J. C. Moon
      Keywords: HFpEF, myocardial fibrosis, T1 mapping

    • ORIGINAL ARTICLES
      Trimetazidine in the new 2016 European guidelines on heart failure and beyond.
      Y. Lopatin
      Keywords: heart failure, guidelines, myocardial metabolism, trimetazidine

    • CASE REPORT
      HFpEF or just multiple comorbidities? The challenges of making a definitive diagnosis.
      J. Webb
      Keywords: cardiac magnetic resonance imaging, HFpEF, pressure-volume loop analysis

    • REFRESHER CORNER
      Heart failure with preserved ejection fraction–where is the problem: heart or arteries?
      S. Ewen, M. Böhm
      Keywords: chronic heart failure, ESC guidelines, heart failure with preserved ejection fraction

    • HOT TOPICS
      The failing heart: an engine operating on “bad” fuel.
      V. Sequeira, J. van der Velden
      Keywords: ADP elevation, cardiac contractility and energetics, cardiomyocyte contractile reserve, diastolic dysfunction

    • GLOSSARY
      G. D. Lopaschuk

    Number 70, 2016, Reducing myocardial infarct size: myth or reality

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    • EDITORIAL
      Burning fat to increase metabolic rates size: myth or reality
      Derek J. Hausenloy, MD, PhD, FACC, FESC
      Read the editorial
    • ORIGINAL ARTICLES
      Reperfusion – the good, the bad, and the ugly
      Gerd Heusch, FACC, FESC, FRCP
      Institute for Pathophysiology, West German Heart and Vascular Center,
      University of Essen Medical School, Essen, Germany
      Keywords: cardioprotection, myocardial ischemia, reperfusion

    • ORIGINAL ARTICLES
      Mechanical interventions to reduce myocardial infarct size
      Michael Rahbek Schmidt, MD, PhD; Nichlas Riise Jespersen, MD; Hans Erik Bøtker, MD, PhD, DMSc
      Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
      Keywords: ischemic preconditioning, myocardial infarction, reperfusion injury

    • ORIGINAL ARTICLES
      How to measure myocardial infarct size by cardiac magnetic resonance imaging
      David Corcoran, BMedSci MRCP; Colin Berry, PhD, FACC, FESC, FRCP
      BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow
      Golden Jubilee National Hospital, Clydebank, UK
      Keywords: acute myocardial infarction, CMR imaging, infarct size

    • ORIGINAL ARTICLES
      Pharmacological agents for reducing myocardial infarct size in ST-segment elevation myocardial infarction
      Thomas Bochaton, MD; François Derimay, MD; Michel Ovize, MD, PhD
      Louis Pradel Hospital, Cardiovascular Functional Exploration Service,
      Clinical Investigation Center & UMR1060 (CarMeN), Claude Bernard University Lyon 1, Lyon, France
      Keywords: ischemia-reperfusion, ST-segment elevation myocardial infarction, treatment of reperfusion injury

    • ORIGINAL ARTICLES
      The cardioprotective effects of trimetazidine
      Petr Widimsky, MD, DrSc, FESC, FACC
      Cardiocenter, Third Faculty of Medicine, Charles University Prague, Czech Republic
      Keywords: angina, cardioprotection; trimetazidine

    • CASE REPORT
      Assessing myocardial salvage in reperfused STEMI patients by hybrid cardiac PET-MR imaging
      Heerajnarain Bulluck, MBBS, MRCP
      The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, UK;
      The National Institute of Health Research University College London Hospitals Biomedical Research Center, UK
      Keywords: myocardial salvage, PET-MR, ST-segment elevation myocardial infarction

    • REFRESHER CORNER
      Metabolic changes in the acutely ischemic heart
      Gary D. Lopaschuk, PhD
      Mazankowski Alberta Heart Institute, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
      Keywords: glycolysis; ischemia, reperfusion
      glycolysis; ischemia, reperfusion
  • HOT TOPICS
    Reducing myocardial infarct size by remote ischemic conditioning
    Luciano Candilio, MD(Res)
    The Hatter Cardiovascular Institute, University College London, London, UK
    Keywords: cardioprotection, myocardial infarction, remote ischemic conditioning

  • GLOSSARY
    Gary D. Lopaschuk